NNB Released its Safety Assessment of MitoBurn® (L-BAIBA): Subchronic Toxicity Study in Sprague Dawley Rats

May 20 18:08 2022

MitoBurn®(L-BAIBA,β-aminoisobutyric acid), known as an exercise factor, increased levels of L-BAIBA are associated with many of exercises numerous benefits. L-BAIBA helps regulate metabolism, increase energy expenditure, manage fuel selection, support the production of ketones,etc.

On May 13, 2022, a toxicity study Published by NNB (https://journals.sagepub.com/doi/abs/10.1177%2F10915818221094487) was designed to evaluate the safety and toxic potentials of MitoBurn(L-BAIBA), where L-BAIBA was administered orally to Sprague Dawley rats at 100, 300, and 900 mg/kg/day for 90 days. The study shows that no treatment-related adverse effects were observed in any of the treatment groups. Based on the results, the No-Observed-Adverse-Effect Level (NOAEL) of L-BAIBA was 900 mg/kg/day. This study is the first study to access the safety profile of L-BAIBA in an in vivo repeated dose subchronic toxicity stud by oral (gavage) route in Sprague Dawley rats.

MitoBurn® L-BAIBA(β-aminoisobutyric acid) , is a signaling molecule secreted by exercising muscles that triggers the adaptive response mechanisms. Increasing L-BAIBA levels augments the results of exercise and provides many of the benefits of regular exercise, without exercising. Many research showed that MitoBurn can improve carb tolerance and insulin sensitivity. L-BAIBA is triggered by the PGC-1α protein from exercising muscles. It plays a powerful role behind the benefits of regular exercise, and initiates the “browning” of white adipose tissue, which increases energy expenditure and helps regulate weight management during EODF (every-other-day fasting). This novel ingredients great for athletes trying to get more out of their workout, casually active individuals looking to amplify diet and workout as well as those looking for healthy ways to get leaner and more fit.

This ingredient is currently favored by a large number of people who enjoy fitness and pay attention to weight management. It’s important to note that this toxicology report published by NNB has never been done by others before. Therefore, this study undoubtedly added great commercial value to MitoBurn®. NNB also believes this study will also allow brand owners who are still on the sidelines to use MitoBurn® with confidence.

Claims About MitoBurn

Decrease body fat and improve body composition

Shown in research to improve carb tolerance and insulin sensitivity

Enhances the body’s exercise signal to intensify exercise efforts

Promotes anti-aging, mitochondrial function, and cellular energy benefits

Increases ketones, promoting cognition, reduced appetite, and muscle protection.

About NNB

NNB is the leading ingredient-driven biotech company employing over 100 research scientists from more than 10 countries who study, design, and deliver unique ingredients to this industry to maximize health, augment performance, expand longevity and enhance appearance. NNB fosters partnerships with companies in the fields of nutraceuticals, pharmaceuticals, and medical research.

Media Contact
Company Name: Nanjing Nutrabuilding Bio-tech Co., LTD. (NNB Nutrition)
Contact Person: Amanda
Email: Send Email
Phone: +86-25 5881 2792
Address:No. 270 Jiqingmen Street, Suning Huigu, Building E6, Room 2105
City: Nanjing
Country: China
Website: https://www.nnbnutrition.com/

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