DelveInsight’s Asthma pipeline report provides comprehensive coverage of the emerging drugs profiles, including clinical and nonclinical products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type.
Key Takeaways from the Asthma Pipeline Report
Get a detailed analysis of the pipeline landscape @ Asthma Pipeline Analysis
Asthma Overview
Asthma is a chronic disease that affects the airways, also known as the bronchial tubes. It is a diverse disease with episodes of airway narrowing or hyperresponsiveness, obstruction, inflammation, and mucous production. The narrowing of the airways causes shortness of breath and coughing. Different inflammatory pathways are responsible for the airway inflammation and hyperresponsiveness associated with asthma.
Asthma Symptoms
Asthma symptoms can vary from person to person. However, the most common asthma symptoms are shortness of breath, wheezing, coughing, and chest tightness. Over time, these symptoms can progress from mild to severe. Asthma symptoms can worsen and cause asthma attacks in some people.
Asthma Treatment
Asthma currently has no cure or specific treatment, but medication and lifestyle changes can help relieve symptoms. Long-term control treatments for asthma, such as inhaled corticosteroids, long-acting beta-agonists, and oral medications, are currently available. Oral corticosteroids, beta-agonists, and inhaled bronchodilators are used to treat acute episodes.
Asthma Pipeline Analysis: Drug Profiles
Depemokimab: GlaxoSmithKline
Product Description
Depemokimab, an Interleukin 5 receptor antagonist monoclonal antibody currently in development by GlaxoSmithKline, is being developed to treat severe asthma with an eosinophilic phenotype.
Phase III
NCT04719832: GlaxoSmithKline initiated a Phase III, 52-week, randomized, double-blind, placebo-controlled, parallel-group, multi-center study of the efficacy and safety of gsk3511294 adjunctive therapy in adults and adolescents with severe uncontrolled asthma with an eosinophilic phenotype in March 2021. gsk3511294 (depemokimab) is being developed as a long-acting (la) injectable anti-interleukin-5 (anti-il-5) therapy with an efficacy and safety profile comparable to current anti-il-5 therapies but with a lower dosing frequency.
Asthma Pipeline Therapies and Key Companies
Find out the emerging therapies and companies @ Asthma Clinical Trials
Asthma Therapeutics Assessment
Scope of the Report
Coverage: Global
Asthma Key Players: GlaxoSmithKline, Oneness Biotech, AstraZeneca, Aquilon Pharma, 4D Pharma PLC, Jiangsu Hengrui Medicine, among others
Asthma Pipeline Therapies: Depemokimab, FB704A, MEDI 3506, AQ001S, MRx-4DP0004, SHR-1703, and others
Table of Contents
1.
Introduction
2.
Executive Summary
3.
Asthma: Overview
4.
Asthma Analytical Perspective In-depth Commercial Assessment
5.
Pipeline Therapeutics
6.
Late Stage Products (Registered)
7.
Late Stage Products (Phase III)
8.
Mid Stage Products (Phase II)
9.
Early Stage Products (Phase I/II)
10.
Early-stage Products (Phase 1)
11.
Therapeutic Assessment
12.
Inactive Products
13.
Company-University Collaborations (Licensing/Partnering) Analysis
14.
Asthma Key Companies
15.
Asthma Key Products
16.
Asthma Unmet Needs
17.
Asthma Market Drivers and Barriers
18.
Asthma Future Perspectives and Conclusion
19.
Asthma Analyst Views
20.
Appendix
21.
About DelveInsight
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Key questions answered in the Asthma Pipeline Report
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